Alfadyn may be available in the countries listed below.
Ingredient matches for Alfadyn
Brimonidine tartrate (a derivative of Brimonidine) is reported as an ingredient of Alfadyn in the following countries:
- Venezuela
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Alfadyn may be available in the countries listed below.
Brimonidine tartrate (a derivative of Brimonidine) is reported as an ingredient of Alfadyn in the following countries:
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Gastidine may be available in the countries listed below.
Cimetidine is reported as an ingredient of Gastidine in the following countries:
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Ciproeptadina may be available in the countries listed below.
Ciproeptadina (DCIT) is known as Cyproheptadine in the US.
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Glossary
DCIT | Denominazione Comune Italiana |
Generic Name: rimabotulinumtoxinB (Myobloc) (RYE ma BOT ue LYE num TOX in B)
Brand Names: Myobloc
RimabotulinumtoxinB (Myobloc), also called botulinum toxin type B, is made from the bacteria that causes botulism. Botulinum toxin blocks nerve activity in the muscles, causing a temporary reduction in muscle activity.
Myobloc is used to treat cervical dystonia (severe spasms in the neck muscles).
Myobloc may also be used for other purposes not listed in this medication guide.
The botulinum toxin contained in this medication can spread to other body areas beyond where it was injected. This has caused serious life-threatening side effects in some people receiving botulism toxin injections, even for cosmetic purposes.
Using this medication more often than prescribed will not make it more effective and may result in serious side effects.
Before receiving a botulinum toxin injection, tell your doctor if you have ALS ( Lou Gehrig's disease), myasthenia gravis, or Lambert-Eaton syndrome.
The effects of a botulinum toxin injection are temporary. Your symptoms may return completely within 3 months after an injection. After repeat injections, it may take less and less time before your symptoms return, especially if your body develops antibodies to the botulinum toxin.
If you have any of these other conditions, you may need a dose adjustment or special tests:
amyotrophic lateral sclerosis (ALS, or "Lou Gehrig's disease");
myasthenia gravis;
Lambert-Eaton syndrome;
a breathing problem such as asthma or emphysema;
problems with swallowing;
bleeding problems;
if you are planning to have surgery; or
if you have ever received other botulinum toxin injections such as Botox or Dysport (especially in the last 4 months).
Myobloc is made using human plasma (part of the blood) and may contain viruses and other infectious agents that can cause disease. Although donated human plasma is screened, tested, and treated to reduce the risk of it containing anything that could cause disease, there is still a small possibility it could transmit disease. Talk with your doctor about the risks and benefits of using this medication.
This medication is injected into a muscle. A doctor, nurse, or other healthcare provider will give you this injection. Myobloc injections should be spaced at least 3 months apart.
Your injection may be given into more than one area at a time, depending on the condition being treated.
Using this medication more often than prescribed will not make it more effective and may result in serious side effects.
Since botulinum toxin has a temporary effect and is given at widely spaced intervals, missing a dose is not likely to be harmful.
Overdose symptoms may not appear right away, but can include muscle weakness, trouble swallowing, and weak or shallow breathing.
The botulinum toxin contained in this medication can spread to other body areas beyond where it was injected. This has caused serious life-threatening side effects in some people receiving botulism toxin injections, even for cosmetic purposes.
trouble breathing, talking, or swallowing;
hoarse voice, drooping eyelids;
unusual or severe muscle weakness (especially in a body area that was not injected with the medication);
loss of bladder control;
problems with vision; or
chest pain.
Less serious side effects may include:
pain or muscle weakness near where the medicine was injected;
headache, joint or back pain;
dry mouth, nausea, upset stomach;
fever, cough, sore throat, flu symptoms;
pain or stiffness in your neck; or
dizziness, drowsiness, anxiety.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Usual Adult Dose for Cervical Dystonia:
Initial: The dose should be individualized based on the patient's head and neck position, localization of pain, muscle hypertrophy, patient response, and adverse event history.
Patients with a prior history of tolerating botulinum toxin injections: 2500 to 5000 units (0.5 to 1.0 mL) divided among affected muscles.
Patients with no history of botulinum toxin type B: use should be at a lower dose, with subsequent dosing based on individual response.
Clinical improvement generally begins within the first two weeks after injection with studies showing the duration of effect to be between 12 and 16 weeks at doses of 5000 units or 10,000 units.
Usual Adult Dose for Hyperhidrosis:
One method being used:
Initial: 2880 units per axilla intradermally for a total dose of 5760 units.
Dilute 5000 unit vial with 1.0 mL of saline in the vial. This dilution technique, when performed in the vial, yields 288 units per 0.1 mL of solution due to the slight overfill in the vial. With this dilution, inject 20 injections of 0.05 mL per axilla may be administered (with an approximate depth of 2 to 3 millimeters), resulting in a total dose of 2880 units per axilla. Injections should be scattered approximately every 2 square centimeters. If injection sites are marked in ink do not inject directly through the ink mark (to avoid a permanent tattoo mark).
Usual Adult Dose for Glabellar Lines:
For glabellar lines and other facial wrinkles: 0.1 mL (500 units) intradermally.
Usual Pediatric Dose for Cervical Dystonia:
The safety and efficacy of botulinum toxin type B for treatment of strabismus in children less than 12 years have not been established.
Initial: The dosage of botulinum toxin type B for the treatment of cervical dystonia should be individualized based on the patient's head and neck position, localization of pain, muscle hypertrophy, patient response, and adverse event history.
Patients with a prior history of tolerating botulinum toxin injections: 2500 to 5000 units (0.5 to 1.0 mL) intramuscularly divided among affected muscles.
Patients with no history of botulinum toxin type B: use should be at a lower dose, with subsequent dosing based on individual response.
Clinical improvement generally begins within the first two weeks after injection with studies showing the duration of effect to be between 12 and 16 weeks at doses of 5000 units or 10,000 units.
Usual Pediatric Dose for Hyperhidrosis:
One method being used:
Initial: 2880 units per axilla intradermally for a total dose of 5760 units.
Dilute 5000 unit vial with 1.0 mL of saline in the vial. This dilution technique, when performed in the vial, yields 288 units per 0.1 mL of solution due to the slight overfill in the vial. With this dilution, inject 20 injections of 0.05 mL per axilla may be administered (with an approximate depth of 2 to 3 millimeters), resulting in a total dose of 2880 units per axilla. Injections should be scattered approximately every 2 square centimeters. If injection sites are marked in ink do not inject directly through the ink mark (to avoid a permanent tattoo mark).
Usual Pediatric Dose for Glabellar Lines:
The safety and efficacy of botulinum toxin type B for treatment of strabismus in children less than 12 years have not been established.
For glabellar lines and other facial wrinkles: 0.1 mL (500 units) intradermally.
Tell your doctor about all other medicines you use, especially:
an antibiotic such as amikacin (Amikin), gentamicin (Garamycin), kanamycin (Kantrex), neomycin (Mycifradin, Neo-Fradin, Neo-Tab), paromomycin (Humatin, Paromycin), streptomycin, tobramycin (Nebcin, Tobi).
This list is not complete and other drugs may interact with Myobloc. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.
See also: rimabotulinumtoxinB side effects (in more detail)
Aspirine C may be available in the countries listed below.
Acetylsalicylic Acid is reported as an ingredient of Aspirine C in the following countries:
Ascorbic Acid is reported as an ingredient of Aspirine C in the following countries:
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